Durataf 25mg isan antiviral medication that contains the active ingredient tenofovir alafenamide (TAF). It is primarily used to treat chronic hepatitis B virus (HBV) infection in adults and adolescents aged 12 and older. It is also used in combination with other antiretroviral drugs to manage HIV-1 infection.
Uses
Chronic Hepatitis B (HBV) infection: Durataf prevents the hepatitis B virus from multiplying in liver cells, which reduces the amount of virus in the body and helps clear the infection.
HIV-1 infection: In HIV-positive individuals, it is used as part of a combination therapy with other antivirals to help control the virus and boost the immune system.
How it works
Tenofovir alafenamide is a "prodrug," meaning it is converted into the active drug, tenofovir diphosphate, inside the cells of the body. The active drug then interferes with the viral polymerase enzyme, which is necessary for the virus to make copies of itself. This process terminates the viral DNA chain and stops the virus from replicating.
Side effects
While most side effects are mild and resolve over time, some may require medical attention.
Common side effects include:
Headache
Nausea and vomiting
Diarrhea
Dizziness
Fatigue
Stomach pain and indigestion
Joint and back pain
Rash or itching
Rare or serious side effects include:
Severe liver problems, which may cause yellowing of the skin or eyes, or dark urine.
Kidney impairment
Lactic acidosis, a build-up of acid in the blood, which can cause unusual tiredness, muscle pain, and difficulty breathing.
Precautions and warnings
Medical history: Inform your doctor if you have kidney or liver disease, HIV infection, or intolerance to some sugars, as these conditions may affect treatment.
Pregnancy and breastfeeding: It is essential to consult with a doctor before using Durataf if you are pregnant, planning a pregnancy, or breastfeeding.
Driving: Since Durataf can cause dizziness, you should avoid driving or operating heavy machinery until you know how the medication affects you.
Alcohol: Avoid drinking alcohol, as it can increase the risk of liver damage.
Never stop abruptly: Do not stop taking the medication without consulting your doctor, as this could worsen your condition and lead to drug resistance.
Preventing transmission: Even while on medication, there is still a risk of transmitting HBV. Always practice safe sex and avoid sharing personal items like needles or razors.
Disclaimer:This is not a substitute for professional medical advice. Always consult a healthcare provider for any health concerns or before starting a new medication.
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