DOLUTEGRAVIR, EMTRICITABINE AND TENOFOVIR ALAFENAMIDE TABLETS
Dosage Form
ONCE-A-DAY
Origin of Medicine
INDIA
Pacakaging (Quantity Per Box)
30
Indication
HIV
Drug Type
Other
Ingredients
Spegra is a brand-name, combination antiretroviral medication used to treat human immunodeficiency virus type 1 (HIV-1) infection in adults and adolescents. It is a once-daily, single-tablet regimen that combines three active ingredients to prevent the virus from multiplying in the body.
Active ingredients and mechanism of action
The three active components in Spegra work synergistically to inhibit different stages of the HIV replication cycle:
Dolutegravir (50 mg): This is an integrase strand transfer inhibitor (INSTI). It blocks the integrase enzyme, which HIV needs to integrate its genetic material into human cells.
Emtricitabine (200 mg): A nucleoside reverse transcriptase inhibitor (NRTI), this drug prevents the viral RNA from being converted into DNA by inhibiting the reverse transcriptase enzyme.
Tenofovir Alafenamide (TAF) (25 mg): This is a nucleotide reverse transcriptase inhibitor (NtRTI) that also blocks the reverse transcriptase enzyme. TAF is a newer formulation of tenofovir with better kidney and bone safety profiles compared to older versions.
Key benefits and uses
Controls HIV-1 infection: Spegra helps suppress the viral load, control the infection, and improve the immune system's function.
Simplifies treatment: As a single tablet taken once daily, it improves treatment adherence and makes managing the condition easier for patients.
Improves quality of life: By reducing HIV-related complications, the medication helps improve the lifespan and overall quality of life for individuals with HIV.
Important considerations
Not a cure for HIV/AIDS: While effective at controlling the virus, Spegra does not cure HIV or AIDS.
Medical supervision required: The medication should be taken exactly as prescribed by a healthcare provider. Stopping treatment abruptly can lead to drug resistance.
Regular monitoring: To monitor the patient's condition and the medication's effect on the body, doctors may recommend regular blood tests to check kidney and liver function.
Common side effects: Potential side effects include insomnia, fatigue, headache, nausea, and diarrhea.
Warnings and precautions: Patients with pre-existing kidney or liver disease should use the medication with caution. It is also important to avoid alcohol consumption and to discuss usage with a doctor if pregnant or breastfeeding.
Physical Form
Tablets
Function
Other
Dosage
ONCE-A-DAY
Dosage Guidelines
AS PER DIOCTOR ADVICE
Suitable For
Women, Adults, Aged Person
Quantity
1 Pieces
Storage Instructions
ROOM TEMPERATURE
SPEGRA TABLETS Trade Information
Minimum Order Quantity
2 Pieces
FOB Port
NEW DELHI
Payment Terms
Cash Advance (CA), Cash in Advance (CID)
Supply Ability
500 Pieces Per Day
Delivery Time
3 Days
Sample Available
No
Sample Policy
Contact us for information regarding our sample policy
Packaging Details
1*30
Main Export Market(s)
Asia
Main Domestic Market
All India
About SPEGRA TABLETS
Spegra isa brand-name, combination antiretroviral medication used to treat human immunodeficiency virus type 1 (HIV-1) infection in adults and adolescents. It is a once-daily, single-tablet regimen that combines three active ingredients to prevent the virus from multiplying in the body.
Active ingredients and mechanism of action
The three active components in Spegra work synergistically to inhibit different stages of the HIV replication cycle:
Dolutegravir (50 mg):This is an integrase strand transfer inhibitor (INSTI). It blocks the integrase enzyme, which HIV needs to integrate its genetic material into human cells.
Emtricitabine (200 mg):A nucleoside reverse transcriptase inhibitor (NRTI), this drug prevents the viral RNA from being converted into DNA by inhibiting the reverse transcriptase enzyme.
Tenofovir Alafenamide (TAF) (25 mg):This is a nucleotide reverse transcriptase inhibitor (NtRTI) that also blocks the reverse transcriptase enzyme. TAF is a newer formulation of tenofovir with better kidney and bone safety profiles compared to older versions.
Key benefits and uses
Controls HIV-1 infection:Spegra helps suppress the viral load, control the infection, and improve the immune system's function.
Simplifies treatment:As a single tablet taken once daily, it improves treatment adherence and makes managing the condition easier for patients.
Improves quality of life:By reducing HIV-related complications, the medication helps improve the lifespan and overall quality of life for individuals with HIV.
Important considerations
Not a cure for HIV/AIDS:While effective at controlling the virus, Spegra does not cure HIV or AIDS.
Medical supervision required:The medication should be taken exactly as prescribed by a healthcare provider. Stopping treatment abruptly can lead to drug resistance.
Regular monitoring:To monitor the patient's condition and the medication's effect on the body, doctors may recommend regular blood tests to check kidney and liver function.
Common side effects:Potential side effects include insomnia, fatigue, headache, nausea, and diarrhea.
Warnings and precautions:Patients with pre-existing kidney or liver disease should use the medication with caution. It is also important to avoid alcohol consumption and to discuss usage with a doctor if pregnant or breastfeeding.
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