Send Inquiry

Request To Call Back

SPEGRA TABLETS

Name: SPEGRA TABLETS
Brand: Ingram Biosciences Pvt. Ltd.
Price: 2562.0 INR
Availability: InStock

Price 2562.0 INR/ Piece

Get a Price/Quote

SPEGRA TABLETS Specification

Dosage Form
ONCE-A-DAY

Origin of Medicine
INDIA

Indication
HIV

Salt Composition
DOLUTEGRAVIR, EMTRICITABINE AND TENOFOVIR ALAFENAMIDE TABLETS

Pacakaging (Quantity Per Box)
30

Drug Type
Other

Ingredients
Spegra is a brand-name, combination antiretroviral medication used to treat human immunodeficiency virus type 1 (HIV-1) infection in adults and adolescents. It is a once-daily, single-tablet regimen that combines three active ingredients to prevent the virus from multiplying in the body. Active ingredients and mechanism of action The three active components in Spegra work synergistically to inhibit different stages of the HIV replication cycle: Dolutegravir (50 mg): This is an integrase strand transfer inhibitor (INSTI). It blocks the integrase enzyme, which HIV needs to integrate its genetic material into human cells. Emtricitabine (200 mg): A nucleoside reverse transcriptase inhibitor (NRTI), this drug prevents the viral RNA from being converted into DNA by inhibiting the reverse transcriptase enzyme. Tenofovir Alafenamide (TAF) (25 mg): This is a nucleotide reverse transcriptase inhibitor (NtRTI) that also blocks the reverse transcriptase enzyme. TAF is a newer formulation of tenofovir with better kidney and bone safety profiles compared to older versions. Key benefits and uses Controls HIV-1 infection: Spegra helps suppress the viral load, control the infection, and improve the immune system's function. Simplifies treatment: As a single tablet taken once daily, it improves treatment adherence and makes managing the condition easier for patients. Improves quality of life: By reducing HIV-related complications, the medication helps improve the lifespan and overall quality of life for individuals with HIV. Important considerations Not a cure for HIV/AIDS: While effective at controlling the virus, Spegra does not cure HIV or AIDS. Medical supervision required: The medication should be taken exactly as prescribed by a healthcare provider. Stopping treatment abruptly can lead to drug resistance. Regular monitoring: To monitor the patient's condition and the medication's effect on the body, doctors may recommend regular blood tests to check kidney and liver function. Common side effects: Potential side effects include insomnia, fatigue, headache, nausea, and diarrhea. Warnings and precautions: Patients with pre-existing kidney or liver disease should use the medication with caution. It is also important to avoid alcohol consumption and to discuss usage with a doctor if pregnant or breastfeeding.

Physical Form
Tablets

Function
Other

Dosage
ONCE-A-DAY

Dosage Guidelines
AS PER DIOCTOR ADVICE

Suitable For
Women, Adults, Aged Person

Quantity
1 Pieces

Storage Instructions
ROOM TEMPERATURE

SPEGRA TABLETS Trade Information

Minimum Order Quantity
2 Pieces

FOB Port
NEW DELHI

Payment Terms
Cash Advance (CA), Cash in Advance (CID)

Supply Ability
500 Pieces Per Day

Delivery Time
3 Days

Sample Available
No

Sample Policy
Contact us for information regarding our sample policy

Packaging Details
1*30

Main Export Market(s)
Asia

Main Domestic Market
All India

About SPEGRA TABLETS

Spegra isa brand-name, combination antiretroviral medication used to treat human immunodeficiency virus type 1 (HIV-1) infection in adults and adolescents. It is a once-daily, single-tablet regimen that combines three active ingredients to prevent the virus from multiplying in the body.

Active ingredients and mechanism of action

The three active components in Spegra work synergistically to inhibit different stages of the HIV replication cycle:

Dolutegravir (50 mg):This is an integrase strand transfer inhibitor (INSTI). It blocks the integrase enzyme, which HIV needs to integrate its genetic material into human cells.
Emtricitabine (200 mg):A nucleoside reverse transcriptase inhibitor (NRTI), this drug prevents the viral RNA from being converted into DNA by inhibiting the reverse transcriptase enzyme.
Tenofovir Alafenamide (TAF) (25 mg):This is a nucleotide reverse transcriptase inhibitor (NtRTI) that also blocks the reverse transcriptase enzyme. TAF is a newer formulation of tenofovir with better kidney and bone safety profiles compared to older versions.

Key benefits and uses

Controls HIV-1 infection:Spegra helps suppress the viral load, control the infection, and improve the immune system's function.
Simplifies treatment:As a single tablet taken once daily, it improves treatment adherence and makes managing the condition easier for patients.
Improves quality of life:By reducing HIV-related complications, the medication helps improve the lifespan and overall quality of life for individuals with HIV.

Important considerations

Not a cure for HIV/AIDS:While effective at controlling the virus, Spegra does not cure HIV or AIDS.
Medical supervision required:The medication should be taken exactly as prescribed by a healthcare provider. Stopping treatment abruptly can lead to drug resistance.
Regular monitoring:To monitor the patient's condition and the medication's effect on the body, doctors may recommend regular blood tests to check kidney and liver function.
Common side effects:Potential side effects include insomnia, fatigue, headache, nausea, and diarrhea.
Warnings and precautions:Patients with pre-existing kidney or liver disease should use the medication with caution. It is also important to avoid alcohol consumption and to discuss usage with a doctor if pregnant or breastfeeding.

Tell us about your requirement

Price:

Quantity

Select Unit

50
100
200
250
500
1000+

Additional detail

Mobile number

More Products in Hepatitis and Anti Viral Category

ENTALIV-0.5 TABLETS

Price 943.0 INR / Piece

Minimum Order Quantity : 2 Pieces

Storage Instructions : ROOM TEMPERATURE

Dosage : ONCEADAY

Origin of Medicine : INDIA

Ingredients : ENTALIV0.5 TABLETS is a brandname medication containing the antiviral drug entecavir, used to treat chronic hepatitis B virus (HBV) infection. It works by preventing the virus from multiplying, thereby reducing the amount of HBV in the body and slowing the progression of liver damage. Key information Active ingredient: Entecavir (0.5 mg). Therapeutic class: Antiviral, specifically a nucleoside reverse transcriptase inhibitor (NRTI). Administration: It is an oral tablet that should be swallowed whole on an empty stomach, at least two hours before or after a meal. Availability: This is a prescription medication. How it works Entaliv0.5 inhibits the viral DNA polymerase enzyme that is essential for the hepatitis B virus to replicate inside liver cells. By blocking this enzyme, entecavir stops the virus from producing new viral particles and controls the infection. Uses ENTALIV0.5 is primarily used to manage chronic HBV infection in adults who show signs of active viral replication and liver inflammation. Important warnings and precautions Not a cure for HBV: It does not cure hepatitis B, but it does help manage the infection and reduce the risk of complications. No prevention of spread: The medication does not prevent the spread of HBV to other people. Safe practices, such as not sharing needles or razors and using condoms, should still be followed. Lactic acidosis: In rare cases, this medication can cause a severe, sometimes fatal condition called lactic acidosis (excess acid in the blood). Symptoms include unusual muscle pain, difficulty breathing, stomach pain, or yellowing of the skin. Obese women are at a higher risk. Worsening hepatitis: Do not stop taking ENTALIV0.5 abruptly without consulting your doctor, as this can lead to a severe worsening of your hepatitis B infection. HIV coinfection: Patients with both HBV and HIV should not use this medication alone. It can cause the HIV virus to develop resistance to certain antiHIV drugs. Liver and kidney function: Your doctor will monitor your liver function and may adjust the dosage if you have kidney problems. Potential side effects The following are common and serious side effects associated with ENTALIV0.5: Common: Headache, fatigue, nausea, vomiting, dizziness, diarrhea, indigestion, and insomnia. Serious (seek immediate medical attention): Allergic reaction: Rash, hives, or swelling of the face, lips, or tongue. Liver problems: Jaundice (yellowing of the skin or eyes), dark urine, or severe stomach pain. Lactic acidosis: Unusual muscle pain, trouble breathing, or fatigue. Who should not take ENTALIV0.5? Tell your doctor before taking this medication if you have a history of: Allergy to entecavir or any of the tablet's ingredients. Severe liver disease or have experienced lactic acidosis. Severe renal (kidney) impairment. Considerations for specific populations Pregnancy: ENTALIV0.5 is a pregnancy category C drug, and its use should be discussed with a doctor to weigh the potential benefits against the risks. Breastfeeding: It is not known if entecavir passes into breast milk. Breastfeeding is not recommended while taking this medication unless your doctor advises otherwise. Children: The tablet is not recommended for children under two years of age. Driving: The medication can cause dizziness and fatigue, so you should avoid driving or operating heavy machinery until you know how it affects you. Alcohol: Avoid consuming alcohol, as it can increase the risk of liver damage. Disclaimer: This is not a substitute for professional medical advice. Always consult a healthcare professional for diagnosis and treatment.

Get a Price/Quote

TENOHEP-AF TABLETS

Price 904.0 INR / Piece

Minimum Order Quantity : 2 Pieces

Storage Instructions : ROOM TEMPERATURE

Dosage : ONCEADAY

Origin of Medicine : INDIA

Ingredients : TENOHEPAF TABLETS are an antiviral medication used to treat chronic Hepatitis B virus (HBV) infection in adults and adolescents. They contain the active ingredient tenofovir alafenamide. How it works Tenofovir alafenamide is a prodrug of tenofovir, meaning it is converted into the active antiviral agent inside the body's cells. The active form blocks a viral enzyme called HBV reverse transcriptase, which is essential for the virus to multiply. By stopping the virus from replicating, TENOHEPAF helps reduce the viral load in the body and clear the infection. Who can take it TENOHEPAF TABLETS are typically prescribed for adults and adolescents (aged 12 and older) with a chronic Hepatitis B virus infection. How to take it Take the tablets exactly as directed by a doctor. Swallow the tablets whole with a glass of water, and do not chew, crush, or break them. Taking the medication with food can increase its absorption. It is crucial to complete the full course of treatment, even if you feel better, unless a doctor advises you to stop. Side effects Common side effects can include: Headache Diarrhea Nausea and vomiting Dizziness Abdominal pain Fatigue Rash Important precautions Medical conditions: Before taking TENOHEPAF, inform your doctor if you have kidney or liver disease, or HIV. Pregnancy and breastfeeding: Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding. Infecting others: This medication does not prevent the spread of the Hepatitis B virus to others. Take precautions to avoid transmission through sexual contact or blood. Driving: The medication may cause dizziness, so avoid driving or operating heavy machinery until you know how it affects you. Alcohol: Avoid drinking alcohol while on this medication, as it may increase the risk of liver damage.

Get a Price/Quote

ENTEHEP-0.5 TABLETS

Price 758.0 INR / Piece

Minimum Order Quantity : 3 Pieces

Storage Instructions : ROOM TEMPERATURE

Dosage : ONCEADAY

Origin of Medicine : INDIA

Ingredients : Entehep0.5 is a brand name for tablets containing the antiviral medication entecavir, which is primarily used to treat chronic hepatitis B virus (HBV) infection. Active ingredient The primary active ingredient in Entehep0.5 is entecavir, in a 0.5 mg dose. Mechanism of action Entecavir is a nucleoside analog that works by inhibiting viral DNA polymerase, an enzyme crucial for the hepatitis B virus to multiply. By blocking this enzyme, the drug prevents the virus from replicating, which reduces the amount of HBV in the body and slows the progression of liver damage. Therapeutic use Entehep0.5 is prescribed for adults and children (typically aged 2 years and older) who have chronic hepatitis B and show signs of active viral replication and liver damage. It helps to manage the infection, improve liver function, and lower the risk of complications such as cirrhosis (liver scarring) and liver cancer. It is important to note that it does not cure hepatitis B. Dosage and administration Take on an empty stomach: The medication is most effective when taken on an empty stomach, at least two hours before or after a meal. Standard dosage: The typical dose for adults is 0.5 mg once daily, but this can vary depending on the individual's condition and previous treatment history. Consistency is key: To maximize effectiveness, patients should take the tablet at the same time every day and not stop taking it suddenly, as this can cause the hepatitis B infection to worsen. Potential side effects Common side effects of entecavir include: Headache Fatigue and extreme tiredness Dizziness Nausea and vomiting Diarrhea Insomnia (difficulty sleeping) Stomach pain More serious, though rare, side effects can include: Lactic acidosis: An excess of lactic acid in the blood, which can be lifethreatening. Symptoms include stomach pain, nausea, and trouble breathing. Liver problems: New or worsening liver issues, including liver enlargement. Severe allergic reaction: Seek immediate medical attention if you experience severe symptoms like swelling or a rash. Important warnings Not a cure: Entehep0.5 does not cure hepatitis B or prevent its transmission to others. Patients should continue practicing safe habits to avoid spreading the virus. HIV coinfection: Patients with both HBV and HIV infections should inform their doctor, as entecavir can cause the HIV infection to develop resistance to certain antiHIV drugs. Kidney or liver problems: Patients with a history of kidney or liver disease should be cautious and may require a dose adjustment. Pregnancy and breastfeeding: Entehep0.5 is typically avoided by pregnant or breastfeeding women unless the potential benefits outweigh the risks. Alcohol: Avoid consuming alcohol during treatment, as it may increase the risk of liver damage.

Get a Price/Quote

TAFERO TABLETS

Price 972.0 INR / Piece

Minimum Order Quantity : 2 Pieces

Storage Instructions : ROOM TEMPERATURE

Dosage : ONCEADAY

Origin of Medicine : INDIA

Ingredients : Tafero tablets are an antiviral medication used to treat chronic Hepatitis B virus (HBV) and Human Immunodeficiency Virus (HIV) infections. Depending on the specific tablet, the active ingredient is either tenofovir alafenamide alone or a combination of tenofovir alafenamide and emtricitabine. Active ingredients Tafero (Tenofovir Alafenamide): This version of the tablet contains tenofovir alafenamide, an antiviral medication that prevents viruses from multiplying in human cells. Tafero EM (Tenofovir Alafenamide and Emtricitabine): This fixeddose combination adds emtricitabine, which also works to block reverse transcriptase, an enzyme necessary for the HIV virus to replicate. How it works As an antiviral, Tafero prevents the virus from replicating, which reduces the viral load in the body. In patients with HIV, this allows the immune system to function better and helps slow the progression of the disease. For individuals with chronic HBV, it works to clear the infection. Primary uses Chronic Hepatitis B (HBV) infection: Treats the viral infection that affects the liver. Human Immunodeficiency Virus (HIV1) infection: Used in combination with other antiretroviral medicines to manage HIV in adults and adolescents weighing at least 35 kg. PreExposure Prophylaxis (PrEP): In some formulations, Tafero is also prescribed to reduce the risk of contracting HIV in highrisk individuals. Potential side effects Common side effects can include: Nausea and vomiting Diarrhea and abdominal pain Headache and dizziness Fatigue or feeling tired Rash or itching Insomnia Less common but more serious side effects may include: Lactic acidosis (buildup of lactic acid in the blood) Severe kidney problems Severe liver problems Bone density issues over longterm use Important considerations Prescription only: Tafero is a prescriptiononly medication and should be taken exactly as directed by a healthcare provider. Not a cure: This medicine controls viral infections but is not a cure for HIV or Hepatitis B. Safe sex: Practicing safe sex is still necessary to prevent the spread of HIV or HBV, even while on this medication. Patient monitoring: Patients should be regularly monitored for liver and kidney function while taking Tafero.

Get a Price/Quote