Dofax 250 Capsules contain the active ingredient dofetilide, a Class III antiarrhythmic medication used to treat irregular heartbeats. It is specifically used to restore and maintain a normal heart rhythm in patients with atrial fibrillation (AF) or atrial flutter (AFL).
Mechanism of action
As a Class III antiarrhythmic, dofetilide works by blocking certain potassium channels in the heart. This action helps to prolong the heart's electrical recovery period, allowing it to beat in a regular and steady rhythm.
Key uses
Conversion: Used to convert atrial fibrillation and atrial flutter back to a normal sinus rhythm.
Maintenance: Used to maintain a normal heart rhythm after a successful conversion.
High-risk treatment: Because of its potential for serious side effects, dofetilide is generally reserved for highly symptomatic patients and must be started under hospital supervision.
Important safety considerations
Hospitalization for initiation: Treatment with dofetilide must begin in a hospital setting for a minimum of three days. This allows doctors to closely monitor the patient's heart rhythm with an electrocardiogram (ECG) and adjust the dosage to minimize the risk of dangerous arrhythmias.
Risk of serious arrhythmia: The most significant risk is developing a life-threatening, irregular heartbeat called Torsades de Pointes. This is the primary reason for the required hospital stay and monitoring.
Kidney function: Dofetilide dosage is critically dependent on kidney function, and adjustments are necessary for patients with reduced kidney clearance. It is contraindicated in patients with severe renal impairment.
Drug interactions: This medication has numerous drug interactions that can increase the risk of serious side effects. Patients must inform their doctor about all prescription and over-the-counter medications, including herbal supplements.
Common side effects
Headache
Dizziness
Chest pain
Nausea and stomach pain
Important warnings
Patients should immediately report signs of an irregular heartbeat, severe dizziness, fainting, or chest pain to their doctor. They should never adjust their dose on their own and should complete the full course of treatment as prescribed.
Physical Form
Capsules
Function
Other
Dosage
ONCE-A-DAY
Dosage Guidelines
AS PER DIOCTOR ADVICE
Suitable For
Women, Adults, Aged Person
Quantity
1 Pieces
Storage Instructions
ROOM TEMPERATURE
DOFAX 250 CAPSULES Trade Information
Minimum Order Quantity
1 Piece
FOB Port
NEW DELHI
Payment Terms
Cash Advance (CA), Cash in Advance (CID)
Supply Ability
500 Pieces Per Day
Delivery Time
3 Days
Sample Available
No
Sample Policy
Contact us for information regarding our sample policy
Packaging Details
3*10
Main Export Market(s)
Asia
Main Domestic Market
All India
About DOFAX 250 CAPSULES
Dofax 250 Capsulescontain the active ingredientdofetilide, a Class III antiarrhythmic medication used to treat irregular heartbeats. It is specifically used to restore and maintain a normal heart rhythm in patients with atrial fibrillation (AF) or atrial flutter (AFL).
Mechanism of action As a Class III antiarrhythmic, dofetilide works by blocking certain potassium channels in the heart. This action helps to prolong the heart's electrical recovery period, allowing it to beat in a regular and steady rhythm.
Key uses
Conversion:Used to convert atrial fibrillation and atrial flutter back to a normal sinus rhythm.
Maintenance:Used to maintain a normal heart rhythm after a successful conversion.
High-risk treatment:Because of its potential for serious side effects, dofetilide is generally reserved for highly symptomatic patients and must be started under hospital supervision.
Important safety considerations
Hospitalization for initiation:Treatment with dofetilide must begin in a hospital setting for a minimum of three days. This allows doctors to closely monitor the patient's heart rhythm with an electrocardiogram (ECG) and adjust the dosage to minimize the risk of dangerous arrhythmias.
Risk of serious arrhythmia:The most significant risk is developing a life-threatening, irregular heartbeat calledTorsades de Pointes. This is the primary reason for the required hospital stay and monitoring.
Kidney function:Dofetilide dosage is critically dependent on kidney function, and adjustments are necessary for patients with reduced kidney clearance. It is contraindicated in patients with severe renal impairment.
Drug interactions:This medication has numerous drug interactions that can increase the risk of serious side effects. Patients must inform their doctor about all prescription and over-the-counter medications, including herbal supplements.
Common side effects
Headache
Dizziness
Chest pain
Nausea and stomach pain
Important warnings Patients should immediately report signs of an irregular heartbeat, severe dizziness, fainting, or chest pain to their doctor. They should never adjust their dose on their own and should complete the full course of treatment as prescribed.
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